Mario Lopez on Longevity, Balance, and Optimizing Health with Hone Health: “Make Wellness Your North Star”

Mario Lopez has worn many hats over the years—actor, television host, husband, and father—but one role he’s become especially passionate about is that of a health advocate. Known for his high-energy lifestyle and dedication to fitness, Mario has always believed that true success starts with taking care of your body and mind. His outlook on health isn’t just about physical appearance; it’s about longevity, vitality, and living with purpose. In this exclusive interview, he sits down with The Advisor’s Stacey Chillemi to share how his personal health journey began, the importance of prevention, and how he maintains balance amid the demands of Hollywood and family life.

At the center of this conversation is Mario’s partnership with Hone Health, a modern health optimization platform designed to help men (and increasingly women) take charge of their well-being through personalized care. Hone Health focuses on proactive, data-driven health by using at-home lab testing to monitor key biomarkers, hormone levels, and overall wellness. The goal is simple: empower people with the knowledge and medical guidance they need to feel their best and live longer, healthier lives. For Mario, Hone Health represents more than just another wellness brand—it’s a movement toward awareness, prevention, and the belief that taking care of yourself today ensures a stronger, more vibrant tomorrow.

Thank you so much for joining us, Mario! Our readers would love to get to know you a bit better. Can you tell us a bit about your backstory?
Thank you for having me. My connection to health really started when I was a baby. I was born healthy, but soon after, I developed serious stomach complications because my digestive system wasn’t fully developed. I made a full recovery, but that early experience stayed with me. I think it subconsciously made me realize that health truly is everything. As I grew older and built my career in entertainment, I always made sure fitness and wellness were at the center of my life. It’s not just about looking good—it’s about feeling good and being able to show up fully for your family and your passions.

You often say that health should be everyone’s top priority. Why do you feel prevention is so important?
When you lose your health, you instantly realize how little everything else matters. Prevention isn’t about fear—it’s about empowerment. Too often, people wait until something goes wrong before they act. But being proactive, staying aware, and taking care of your body before there’s a problem can completely change your quality of life. You can’t control everything, but you can control your habits and your awareness.

You recently partnered with Hone Health. For those who may not know, what exactly is Hone Health?
Hone Health is a company that helps people take control of their health by focusing on awareness, optimization, and prevention. They use at-home blood testing and medical guidance to help you understand what’s going on inside your body—everything from hormone levels to essential biomarkers. Once you know that information, you can make educated decisions about how to improve your energy, balance your hormones, and live better overall. It’s all about knowledge, empowerment, and longevity.

What inspired you to collaborate with Hone Health?
We share the same values. Hone Health’s approach to preventive care and optimization aligns perfectly with how I live my life. They believe in putting health first, being proactive, and helping people understand what’s going on inside their bodies. I’ve always been focused on longevity—I want to feel great, stay strong, and be here for my kids and their kids. Hone Health gives people access to the tools and support they need to make that possible.

Since you’ve been working with Hone Health, what kind of changes have you experienced personally?
It’s been empowering. The biggest difference is having real insight into my body. Before, I was mostly going off how I felt. Now, I can see what’s really happening with my hormones, energy levels, and recovery. That knowledge gives me confidence—it helps me make smarter decisions about my fitness, nutrition, and sleep. When you understand your body on a deeper level, you naturally start taking better care of it.

A lot of people in their 30s, 40s, and 50s notice their bodies changing but aren’t sure where to start. What advice would you give them?
First, it’s never too late to take control of your health. That’s the most important thing to understand. Start by making small changes and being consistent. Get curious about what’s going on with your body. Pay attention to your hormones, energy, and recovery. And do it for the people you love, too—your family, your friends. When you feel your best, you show up better for everyone around you.

You have a demanding career and a family. How do you stay balanced while keeping your health a top priority?
It comes down to routine. No matter how early my day starts, I make time to move my body. I usually work out in the morning—it sets the tone for everything that follows. Once I’ve done that, I can be more present for work and family. Exercise isn’t just physical for me—it keeps me grounded and focused. I also try to be intentional about rest, time with my wife and kids, and not spreading myself too thin.

How does nutrition fit into your overall approach to health?
Nutrition is a big part of it, but I keep things simple. I don’t count calories—I just focus on balance. Every plate should have protein, healthy carbs, and good fats. That’s really the foundation. I think it’s about consistency more than perfection. And I believe in having something to look forward to—a favorite meal or treat on the weekend keeps you motivated and balanced.

Hone Health works a lot with hormonal optimization. Why is that such an important part of wellness as we age?
Hormones are everything. They impact your energy, mood, focus, metabolism, and even your motivation to work out. As we get older, those levels start to shift, and understanding them can make all the difference. Hone Health helps you see what’s going on so you can make adjustments before problems start. It’s not just for men—women can benefit too. It’s about taking control of your body, not letting it run the show.

You’re known for your dedication to fitness. How often do you work out, and what motivates you to stay consistent?
I try to work out every day, or at least six days a week. I honestly don’t feel like I’ve fully started my day until I break a sweat. It clears my head and sets a positive tone. Fitness helps with more than just my physical health—it’s a huge stress reliever and a way to stay sharp mentally. If I skip a workout, I feel it not just in my body but in my mindset, too.

Some people think they need to work out for hours to see results. What’s your take on that?
That’s one of the biggest myths. You don’t need a long workout—what matters is consistency. Start small. Even 15 or 20 minutes a day of movement adds up over time. Walk, stretch, lift, dance—whatever gets you moving. Once you build momentum, it becomes part of your lifestyle. It’s not about perfection, it’s about progress.

Mental health is just as important as physical health. How do you manage your stress and maintain mental clarity?
For me, prayer and quiet time are essential. I take moments throughout the day to reflect and give thanks—it grounds me. That stillness helps me stay focused and grateful. You can’t pour from an empty cup, so I make sure to recharge mentally and spiritually as much as I do physically.

If someone wanted to start improving their health but didn’t know where to begin, what five things would you tell them?
First, get your mindset right—you have to decide that you want to change.
Second, commit to small daily habits.
Third, move your body every day—it doesn’t matter how long.
Fourth, eat a balanced plate with real food.
And fifth, get your blood work done. Learn what’s happening in your body so you’re not guessing. That’s where companies like Hone Health come in—they help you personalize your approach so you can get the best results.

Many people find themselves caught in a cycle of medications and side effects. What do you think about finding more natural approaches to health?
That’s what I love most about Hone Health. They encourage people to understand their biology first before turning to medication. You can often address so many issues through lifestyle changes, nutrition, and optimizing your hormones naturally. It’s not about avoiding doctors—it’s about working smarter with the information you have and supporting your body instead of masking the symptoms.

You recently attended the Dreamchasers 5K and the recovery event at Othership. What’s your go-to method for recovery after a workout or event like that?
I’m a big believer in recovery. My go-to is contrast therapy—sauna and cold plunges. It’s great for circulation, muscle recovery, and mental reset. I also focus on getting good sleep, staying hydrated, and stretching daily. Recovery is part of training—it’s how your body rebuilds and gets stronger.

What’s one health myth you wish people would stop believing?
That you have to be perfect to be healthy. You don’t. You just have to be consistent. People often get discouraged because they slip up or miss a day, but health isn’t all or nothing. It’s about showing up, doing your best, and building habits you can sustain.

You travel a lot for work. How do you maintain your healthy lifestyle on the road?
Preparation is everything. I pack resistance bands, use hotel gyms, and make movement part of my day—sometimes that just means walking more. I also try to eat balanced meals, drink plenty of water, and sleep when I can. You can’t always control your environment, but you can control your effort.

You’re a dad—how do you encourage healthy habits in your kids?
We make it fun. Whether it’s playing sports, hiking, or cooking together, we turn wellness into something they enjoy. Kids mirror what they see. If they see you making healthy choices, it becomes normal to them. I want them to understand that health is a lifestyle, not a chore.

For those interested in Hone Health, what does the process look like when someone gets started?
It’s simple and accessible. You start with a home blood test to check your hormone levels and key biomarkers. Once your results are in, Hone Health’s medical team explains what they mean and creates a personalized plan. It’s designed to make optimization easy and sustainable, even for people who are new to this.

When you talk about longevity, what does that mean to you personally?
Longevity isn’t just about living longer—it’s about living well. I want to have energy for my work, patience for my family, and strength to handle life’s challenges. For me, it’s about quality of life. Every healthy choice I make today helps create a better tomorrow.

Any final thoughts or advice for readers who are ready to start taking their health seriously?
Start now. You don’t have to wait for a perfect moment or for something to go wrong. Take small steps—move your body, eat mindfully, get your blood work done, and build consistency. The payoff isn’t just a longer life—it’s a better one.

Thank you so much for joining us today, Mario. This has been such an inspiring and uplifting conversation—I know our readers will walk away feeling motivated to take better care of themselves.
Thank you! I really enjoyed our chat. I appreciate the opportunity to share something I’m truly passionate about. Health is the foundation for everything, and I’m grateful we got to spread that message together—and make sure to check out Hone Health to see how you can start optimizing your own wellness journey.

Listen to our full conversation with Mario Lopez on The Advisor podcast, available on YouTube, Spotify, and Apple Podcasts—and to learn more about optimizing your own health, visit www.honehealth.com for personalized, at-home wellness solutions.