Sophia Bush says the blueprint for how she lives her life can be found in the quote, “You are allowed to be both a masterpiece and a work in progress, simultaneously.” For the debut episode of the new season of the Thrive Global Podcast, the actor (“One Tree Hill,” “Chicago P.D.”) and entrepreneur-activist sits down with Arianna Huffington for a candid conversation about the aftermath of failure, the freedom in hitting reset, social activism, and her own new podcast.

Check out the rest of The Thrive Global Podcasts, sponsored by Crest 3D White and in partnership with iHeartRadio, here. To find out more, listen to the full conversation on iHeartRadio, here. You can also listen to the Thrive Global Podcast internationally for free on iTunes.